EmBioSys Lab
Publications

Publications


2024

L. W. Honaker*, A. Eijffius*, L. Plankensteiner, C. V. Nikiforidis, and S. Deshpande.
Biosensing with Oleosin-Stabilized Liquid Crystal Droplets
Small, 2309053, 2024.

N. Appelman, C. Chen, I. Gruppen, and S. Deshpande.
Interface-Driven Spontaneous Differentiation-Repulsion Behaviour in Isochemical Droplet Populations
Advanced Materials Interfaces, 2024.


2023

K. A. Ganar, P. Turbina, M. Nandy, C. Chen, D. Suylen, E. L. Pascoe, C. J. M. Koenraadt, I. Dijkgraaf§, and S. Deshpande§.
Phase Separation and Ageing of Glycine-Rich Protein from Tick Adhesive
bioRxiv, 2023.

R. J. de Haas, K. A. Ganar, S. Deshpande, and R. de Vries.
pH-Responsive Elastin-Like Polypeptide Designer Condensates
ACS Applied Materials and Interfaces, 15(38):45336-45344, 2023.

K. Aryan, K. A. Ganar, S. Deshpande, R. M. Boom, and C. V. Nikiforidis.
Continuous counter-current electrophoretic separation of oleosomes and proteins from oilseeds
Food Hydorcolloids, 144:109053, 2023.

L. W. Honaker, J. Schaap, D. Kenbeek, E. Miltenburg, and S. Deshpande.
Heads or Tails: Investigating the Effects of Amphiphile Features on the Distortion of Chiral Nematic Liquid Crystal Droplets
Journal of Materials Chemistry C, 11:4867–4875, 2023.

C. Chen, K. A. Ganar, and S. Deshpande.
On-Chip Octanol-Assisted Liposome Assembly for Bioengineering
Journal of Visualised Experiments, 193:e65032, 2023.


2022

C. Chen, H. Meng, T. Guo, S. Deshpande, and H. Chen.
Development of Paper Microfluidics with 3D-Printed PDMS Barriers for Flow Control
ACS Applied Materials and Interfaces, 14(35):40286–40296, 2022.

L. W. Honaker, C. Chen, F. M. H. Dautzenberg, S. Brugman, and S. Deshpande.
Designing Biological Microsensors with Chiral Nematic Liquid Crystal Droplets
ACS Applied Materials and Interfaces, 14(33):37316–37329, 2022.

K. A. Ganar, L. Leijten, and S. Deshpande.
Actinosomes: condensate-templated containers for engineering synthetic cells
ACS Synthetic Biology, 11(8):2869–2879, 2022.

E. Bouzetos, K. A. Ganar, E. Mastrobattista, S. Deshpande§, and J. van der Oost§.
(R)evolution-on-a-chip
Trends in Biotechnology, 40(1):60-76, 2022.


2021

K. A. Ganar, L. W. Honaker, and S. Deshpande.
Shaping Synthetic Cells Through Cytoskeleton-Condensate-Membrane Interactions
Current Opinion in Colloid and Interface Science, 54:101459, 2021.

S. Deshpande§ and C. Dekker§.
Studying Phase Separation in Confinement
Current Opinion in Colloid and Interface Science, 52:101419, 2021.


2020

M. G. F. Last*, S. Deshpande*, and C. Dekker.
pH-controlled coacervate-membrane interactions within liposomes.
ACS Nano, 14(4):4487-4498, 2020.


2019

S. Deshpande and C. Dekker.
Synthetic life on chip.
Emerging Topics in Life Sciences, ETLS20190097, 2019.

S. Deshpande, S. Wunnava, D. Hueting, and C. Dekker.
Membrane tension-mediated growth of liposomes.
Small, 15(38):e1902898, 2019.

F. Fanalista*, A. Birnie*, K. Charles, G. Pawlik, R. Maan, F. Burla, S. Deshpande, G. Koenderink, M. Dogterom, and C. Dekker.
Shape and size control of artificial cells for bottom-up biology.
ACS Nano, 13(5):5439–5450, 2019.

M. Schaich, J. Cama, K. Al Nahas, D. Sobota, K. Jahnke, S. Deshpande, C. Dekker, and U. F. Keyser.
An integrated microfluidic platform for quantifying drug permeation across biomimetic vesicle membranes.
Molecular Pharmaceutics, 16(6):2494–2501, 2019.

S. Deshpande, F. Brandenburg*, A. Lau*, M.G.F. Last, K. Spoelstra, S. Wunnava, L. Reese, M. Dogterom, and C. Dekker.
Spatiotemporal control of coacervate formation within liposomes.
Nature Communications, 10:1800, 2019.

K. Al Nahas, J. Cama, M. Schaich, K. Hammond, S. Deshpande, C. Dekker, M. G. Ryadnov, and U. F. Keyser.
A microfluidic platform for the characterisation of membrane active antimicrobials.
Lab on a Chip, 19(5):837–844, 2019.


2018

F. Fanalista*, S. Deshpande*, A. Lau, G. Pawlik, and C. Dekker.
FtsZ-induced shape transformation of coacervates.
Advanced Biosystems, 1800136, 2018.

S. Deshpande and C. Dekker.
On-chip microfluidic production of cell-sized liposomes.
Nature Protocols, 13:856–874, 2018.

S. Deshpande, W. K. Spoelstra, M. van Doorn, J. Kerssemakers, and C. Dekker.
Mechanical division of cell-sized liposomes.
ACS Nano, 12(3):2560–2568, 2018.

M. Kaiser*, F. Jug*, T. Julou*, S. Deshpande, T. Pfohl, O. Silander, G. Myers, and E. van Nimwegen.
Monitoring single-cell gene regulation under dynamically controllable conditions with integrated microfluidics and software.
Nature Communications, 9:212, 2018.

W. K. Spoelstra*, S. Deshpande*, and C. Dekker
Tailoring the appearance: what will synthetic cells look like?
Current Opinion in Biotechnology, 51:47-56, 2018.


2017

I. Hug, S. Deshpande, K. Sprecher, T. Pfohl, and U. Jenal.
Second messenger-mediated tactile response by a bacterial rotary motor.
Science, 358:531–534, 2017.

S. Deshpande, A. Birnie, and C. Dekker.
On-chip density-based purification of liposomes.
Biomicrofluidics, 11:034106, 2017.


2016

M. Göllner, A. C. Toma, N. Strelnikova, S. Deshpande, and T. Pfohl.
A self-filling microfluidic device for noninvasive and time-resolved single red blood cell experiments.
Biomicrofluidics, 10:054121, 2016.

S. Deshpande, Y. Caspi, A. Meijering, and C. Dekker
Octanol-assisted liposome assembly on chip.
Nature Communications, 7:10447, 2016.


2015

Z. Swank, S. Deshpande, and T. Pfohl.
Trapping, entrainment and synchronization of semiflexible polymers in narrow, asymmetric confinements.
Soft Matter, 12:87–92, 2015.

A. Hochstetter, E. Stellamanns, S. Deshpande, S. Uppaluri, M. Engstler, and T. Pfohl.
Microfluidics-based single cell analysis reveals drug-dependent motility changes in trypanosomes.
Lab on a Chip, 15(8):1961–8, 2015.

S. Deshpande and T. Pfohl.
Real-time dynamics of emerging actin networks in cell-mimicking compartments.
PLoS ONE, 10(3):e0116521, 2015.


2012

S. Deshpande and T. Pfohl
Hierarchical self-assembly of actin in microconfinements using microfluidics.
Biomicrofluidics, 6:034120, 2012.


* denotes equal contribution, § denotes shared correspondence.